Tuesday, April 2, 2013

New models predict drastically greener Arctic in coming decades

Monday, April 1, 2013

New research predicts that rising temperatures will lead to a massive "greening," or increase in plant cover, in the Arctic. In a paper published on March 31 in Nature Climate Change, scientists reveal new models projecting that wooded areas in the Arctic could increase by as much as 50 percent over the next few decades. The researchers also show that this dramatic greening will accelerate climate warming at a rate greater than previously expected.

"Such widespread redistribution of Arctic vegetation would have impacts that reverberate through the global ecosystem," said Richard Pearson, lead author on the paper and a research scientist at the American Museum of Natural History's Center for Biodiversity and Conservation.

Plant growth in Arctic ecosystems has increased over the past few decades, a trend that coincides with increases in temperatures, which are rising at about twice the global rate. The research team?which includes scientists from the Museum, AT&T Labs-Research, Woods Hole Research Center, Colgate University, Cornell University, and the University of York?used climate scenarios for the 2050s to explore how this trend is likely to continue in the future. The scientists developed models that statistically predict the types of plants that could grow under certain temperatures and precipitation. Although it comes with some uncertainty, this type of modeling is a robust way to study the Arctic because the harsh climate limits the range of plants that can grow, making this system simpler to model compared to other regions such as the tropics.

The models reveal the potential for massive redistribution of vegetation across the Arctic under future climate, with about half of all vegetation switching to a different class and a massive increase in tree cover. What might this look like? In Siberia, for instance, trees could grow hundreds of miles north of the present tree line.

"These impacts would extend far beyond the Arctic region," Pearson said. "For example, some species of birds seasonally migrate from lower latitudes and rely on finding particular polar habitats, such as open space for ground-nesting."

In addition, the researchers investigated the multiple climate change feedbacks that greening would produce. They found that a phenomenon called the albedo effect, based on the reflectivity of the Earth's surface, would have the greatest impact on the Arctic's climate. When the sun hits snow, most of the radiation is reflected back to space. But when it hits an area that's "dark," or covered in trees or shrubs, more sunlight is absorbed in the area and temperature increases. This has a positive feedback to climate warming: the more vegetation there is, the more warming will occur.

"By incorporating observed relationships between plants and albedo, we show that vegetation distribution shifts will result in an overall positive feedback to climate that is likely to cause greater warming than has previously been predicted," said co-author Scott Goetz, of the Woods Hole Research Center.

###

American Museum of Natural History: http://www.amnh.org

Thanks to American Museum of Natural History for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127537/New_models_predict_drastically_greener_Arctic_in_coming_decades

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Friending your boss on Facebook

How often do you normally use social media? graph of japanese statisticsjapan.internet.com recently reported on an interesting survey conducted by Nifty, comnico and Lifemedia into social media usage, focusing on young soon-to-graduate students.

Demographics

Between the 8th and 11th of March 2013 559 social media-using people who were due to graduate at the end of this academic year and were aged between 20 and 26 completed an internet survey, but it was not reported how the sample was gathered. 62.1% of the sample were female, and 37.9% male.

Coincidentally, my new group leader today introduced himself, including his Facebook page, and suggested that people interested should befriend him, so I shall do that and see what happens?

Research results

First of all, not reported in graphs but as text was that the top three most often used social media (SNS, chat, Twitter, etc) were first Twitter with 41.0%, second LINE (chat) with 31.5%, and third Facebook with 20.8%, leaving all the rest with just 16.7% between them. The sex split for Twitter was not reported, perhaps due to no significant difference, but LINE was most popular with 35.7% of women versus 24.5% of men, whereas Facebook was 24.5% for men and 18.4% for women.

Q1: How often do you normally use social media? (Sample size=559)

Many times a day 64.6%
Once a day 17.7%
Once every two or three days 8.9%
Once a week 5.2%
Once a month 2.3%
Once every several months 0.7%
Once a year or less 0.5%

Q2: When you start working, do you think you will try to friend your boss, seniors? (Sample size=559)

Will proactively friend them (to SQ2) 6.1%
Depends on the service (to SQ1, SQ2) 35.1%
Avoid as much as possible 58.9%

Q2SQ1: Do you think you will try to friend your boss, seniors on the following services? (Sample size=196)

? Proactively Avoid if possible Don?t use it
Twitter 13.8% 56.1% 30.1%
Facebook 43.4% 34.2% 22.4%
LINE 29.1% 36.7% 34.2%
mixi 7.7% 40.8% 51.5%
Other 0.0% 1.0% 99.0%

Q2SQ2: If your boss, seniors try to friend you on the following services, will you accept? (Sample size=239)

? Proactively Avoid if possible Don?t use it
Twitter 13.0% 58.6% 28.5%
Facebook 35.1% 34.7% 30.1%
LINE 36.4% 29.7% 33.9%
mixi 10.9% 33.9% 55.2%
Other 0.0% 0.8% 99.2%

Q3: Would you like to use social media at work to build up your human network, gather information, etc? (Sample size=559)

Think so 6.6%
Perhaps think so 31.3%
Don?t really think so 36.3%
Don?t think so at all 25.8%
Read more on: comnico,facebook,lifemedia,line,nifty,twitter

Permalink

Source: http://feedproxy.google.com/~r/WhatJapanThinks/~3/qBT8VIzRVGA/

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Limited-Edition Jar Jar Binks Thumbdrive Costs You Nerd Cred

Limited-Edition Jar Jar Binks Thumbdrive Costs You Nerd Cred
The most hated Star Wars character ever is coming to a USB port near you. For reals this time.

Source: http://www.wired.com/gadgetlab/2013/04/jar-jar-noooo/

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Monday, April 1, 2013

Aereo wins a crucial court battle, opens up partnership talks with ISPs and pay-TV providers

Aereo wins a crucial court battle, opens up partnership talks with ISPs and payTV providers

Something tells us the US Court of Appeals for the Second District has no intentions to kid around with its latest decision, despite it coming down on the 1st of April. In what can only be viewed as a monumental victory for Aereo, the aforesaid court has just rejected an appeal from a smattering of TV networks that are hellbent on stopping the web-streaming company from treading on their territory. For those unaware, Aereo allows users to stream OTA television networks over the web, but this here court found that the system did not infringe on the broadcasters' copyrights. Of course, a battle at the Supreme Court level is a practical certainty, so it's definitely not out of the proverbial woods just yet.

That said, a separate Wall Street Journal report sheds light on ongoing discussions between the startup and some very established players in the industry -- if you can't beat 'em, join' em... right? As the story goes, AT&T, Dish Network and DirecTV have all spoken with Aereo as the company hopes to expand its footprint beyond New York City and the surrounding areas. On one hand, a mega-corp swallowing Aereo could lead to near-instant demise for its technologies, but given the right owner, it could provide the disruption the pay-TV sector so badly needs.

Filed under: ,

Comments

Via: TechCrunch, The Verge

Source: US Court of Appeals for the Second Circuit [PDF], WSJ

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/8H0Z-ySlpnc/

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Princess Margaret breast cancer research finds new drug target companion prognostic test for hormone therapy resistance

Princess Margaret breast cancer research finds new drug target companion prognostic test for hormone therapy resistance [ Back to EurekAlert! ] Public release date: 1-Apr-2013
[ | E-mail | Share Share ]

Contact: Jane Finlayson
jane.finlayson@uhn.ca
416-946-2846
University Health Network

(TORONTO, Canada April 1, 2013) A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive breast cancer cells that are resistant to hormone therapies such as tamoxifen, aromatase inhibitors or fulvestrant.

Resistance to hormone therapy is reported in almost half of ER-positive breast cancer patients and no cure is currently available. The fact that the pathway, called Notch, is a drug target creates hope for a new therapy.

The findings, published online today in PNAS, the Proceedings of the National Academy of Sciences of the United States of America, "provide a new therapeutic target against hormone therapy-resistant breast cancers and a companion test to identify tumours that would become resistant" says Dr. Lupien, a scientist at the Ontario Cancer Institute, the research arm of the cancer centre, and an Assistant Professor in the Department of Medial Biophysics, University of Toronto. He specializes in epigenetics of hormone-dependent cancers the study of non-genetic determinants of cellular identity that can also be altered to initiate or modify disease.

"In studying the epigenetics of hormone therapy resistance, we discovered that breast cancer cells behave like a chameleon. Indeed, as the chameleon changes its skin colour to camouflage itself and evade predators," says Dr. Lupien, "breast cancer cells change the appearance of their DNA through epigenetics to evade, in this case, hormone therapy." In so doing, hormone therapy-resistant breast cancer cells highlight regions of their DNA related to the Notch pathway.

At the molecular level, the research team characterized the epigenetic appearances of the DNA of drug-resistant and drug-responsive breast cancer cells. The team discovered that the Notch signaling pathway plays the predominant role in drug-resistant breast cancer cells even if cells remain positive for ER.

"This is a highly promising discovery that could rapidly translate in the clinic. Drugs against the Notch pathway are available." says Dr. Lupien. The key will be to test the efficacy of these drugs against hormone therapy resistance in breast cancer.

###

The research was funded by the National Cancer Institute, the American Cancer Society and the Ontario Institute for Cancer Research. Dr. Lupien's research is also supported by The Princess Margaret Cancer Foundation.

About the Princess Margaret Cancer Centre, University Health Network

The Princess Margaret Cancer Centre and its research arm, Ontario Cancer Institute, which includes The Campbell Family Cancer Research Institute, have achieved an international reputation as global leaders in the fight against cancer and delivering personalized cancer medicine. The Princess Margaret, one of the top five international cancer research centres, is a member of the University Health Network, which also includes Toronto General Hospital, Toronto Western Hospital and Toronto Rehabilitation Institute. All are research hospitals affiliated with the University of Toronto. For more information, go to http://www.theprincessmargaret.ca or http://www.uhn.ca.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Princess Margaret breast cancer research finds new drug target companion prognostic test for hormone therapy resistance [ Back to EurekAlert! ] Public release date: 1-Apr-2013
[ | E-mail | Share Share ]

Contact: Jane Finlayson
jane.finlayson@uhn.ca
416-946-2846
University Health Network

(TORONTO, Canada April 1, 2013) A team of international cancer researchers led by Dr. Mathieu Lupien at the Princess Margaret Cancer Centre, University Health Network, has identified the signalling pathway that is over-activated in estrogen receptor (ER)-positive breast cancer cells that are resistant to hormone therapies such as tamoxifen, aromatase inhibitors or fulvestrant.

Resistance to hormone therapy is reported in almost half of ER-positive breast cancer patients and no cure is currently available. The fact that the pathway, called Notch, is a drug target creates hope for a new therapy.

The findings, published online today in PNAS, the Proceedings of the National Academy of Sciences of the United States of America, "provide a new therapeutic target against hormone therapy-resistant breast cancers and a companion test to identify tumours that would become resistant" says Dr. Lupien, a scientist at the Ontario Cancer Institute, the research arm of the cancer centre, and an Assistant Professor in the Department of Medial Biophysics, University of Toronto. He specializes in epigenetics of hormone-dependent cancers the study of non-genetic determinants of cellular identity that can also be altered to initiate or modify disease.

"In studying the epigenetics of hormone therapy resistance, we discovered that breast cancer cells behave like a chameleon. Indeed, as the chameleon changes its skin colour to camouflage itself and evade predators," says Dr. Lupien, "breast cancer cells change the appearance of their DNA through epigenetics to evade, in this case, hormone therapy." In so doing, hormone therapy-resistant breast cancer cells highlight regions of their DNA related to the Notch pathway.

At the molecular level, the research team characterized the epigenetic appearances of the DNA of drug-resistant and drug-responsive breast cancer cells. The team discovered that the Notch signaling pathway plays the predominant role in drug-resistant breast cancer cells even if cells remain positive for ER.

"This is a highly promising discovery that could rapidly translate in the clinic. Drugs against the Notch pathway are available." says Dr. Lupien. The key will be to test the efficacy of these drugs against hormone therapy resistance in breast cancer.

###

The research was funded by the National Cancer Institute, the American Cancer Society and the Ontario Institute for Cancer Research. Dr. Lupien's research is also supported by The Princess Margaret Cancer Foundation.

About the Princess Margaret Cancer Centre, University Health Network

The Princess Margaret Cancer Centre and its research arm, Ontario Cancer Institute, which includes The Campbell Family Cancer Research Institute, have achieved an international reputation as global leaders in the fight against cancer and delivering personalized cancer medicine. The Princess Margaret, one of the top five international cancer research centres, is a member of the University Health Network, which also includes Toronto General Hospital, Toronto Western Hospital and Toronto Rehabilitation Institute. All are research hospitals affiliated with the University of Toronto. For more information, go to http://www.theprincessmargaret.ca or http://www.uhn.ca.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-04/uhn-pmb032813.php

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Shain Gandee: Remembering 'Buckwild' Star's 'Passion For Life'

In a January interview, Gandee told MTV News his life was 'pretty fun,' and he wanted it to stay that way.
By James Montgomery


Shain Gandee
Photo: MTV News

Source: http://www.mtv.com/news/articles/1704734/shain-gandee-buckwild-life.jhtml

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3 killed in 75-vehicle pileup at Virginia-NC line

GALAX, Va. (AP) ? Virginia State Police say three people have been killed and more than 20 are injured following a 75-vehicle pileup on Interstate 77 near the Virginia-North Carolina border.

The Virginia Department of Transportation says traffic is backed up about 8 miles.

State police say a series of wrecks began around 1:15 p.m. Sunday in the southbound lanes in the area of Fancy Gap Mountain in southwest Virginia. There was heavy fog at the time.

State police spokeswoman Corinne Geller says several vehicles caught fire, but the blazed has been put out.

The interstate is closed in both directions. Northbound lanes are closed so emergency vehicles can get to the southbound lanes.

Motorists are being advised to seek alternate routes.

Source: http://news.yahoo.com/3-killed-75-vehicle-pileup-virginia-nc-line-195155232.html

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